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Ingredient Analysis: Acetylsalicyloyl Pentapeptide-33

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unlock the secrets of Acetylsalicyloyl Pentapeptide-33 (pronounced as a-cetyl-salicyloyl penta-peptide-33), a complex cosmetic ingredient with antioxidant and skin-protecting properties, its production process, benefits, and safety profile in our comprehensive guide.

What is Acetylsalicyloyl Pentapeptide-33?

Acetylsalicyloyl Pentapeptide-33 is a complex cosmetic ingredient derived from the reaction of Acetylsalicylic Acid, commonly known as Aspirin, and Pentapeptide-33. This compound is also known by its INCI name, Acetylsalicyloyl Pentapeptide-33, and is recognized for its antioxidant and skin-protecting properties.

The use of Acetylsalicyloyl Pentapeptide-33 in cosmetic products is a relatively recent development. Its creation was inspired by the well-documented benefits of Aspirin, a salicylate drug with anti-inflammatory and pain-relieving properties. Scientists sought to harness these benefits in a form that could be utilized in skincare, leading to the development of Acetylsalicyloyl Pentapeptide-33.

The production of Acetylsalicyloyl Pentapeptide-33 involves a chemical reaction between Acetylsalicylic Acid and Pentapeptide-33. This process results in a compound that combines the beneficial properties of both its parent substances, offering enhanced skin protection and antioxidant benefits.

While there are other ingredients that offer similar benefits, such as Retinol and Vitamin C, Acetylsalicyloyl Pentapeptide-33 stands out due to its unique composition. Unlike these other ingredients, it is derived from a combination of a well-known drug (Aspirin) and a peptide, which gives it a unique profile of benefits.

Acetylsalicyloyl Pentapeptide-33 is typically used in a variety of skincare products, including moisturizers and serums. Its antioxidant properties make it particularly beneficial in products designed to protect the skin from environmental stressors, while its skin-protecting benefits make it a valuable addition to products aimed at improving skin health and appearance.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Acetylsalicyloyl Pentapeptide-33:

Antioxidant Properties

Acetylsalicyloyl Pentapeptide-33 is officially recognized for its antioxidant properties. In layman’s terms, this means it helps protect your skin from damage caused by harmful molecules known as free radicals. These free radicals are produced by environmental factors like pollution, UV rays, and even the stress of everyday life. By neutralizing these free radicals, Acetylsalicyloyl Pentapeptide-33 can help prevent premature aging and maintain the health and vitality of your skin.

Skin Protecting Abilities

Another officially recognized function of Acetylsalicyloyl Pentapeptide-33 is its skin protecting abilities. This means it forms a protective barrier on the skin’s surface, shielding it from harmful environmental factors. This barrier not only protects the skin from damage but also helps to maintain its moisture levels, leading to healthier, more hydrated skin. This can be particularly beneficial for those with dry or sensitive skin types.

Please note that these benefits are based exclusively on the officially recognized and defined functions of Acetylsalicyloyl Pentapeptide-33. There may be other benefits and uses that go beyond the scope of these official functions. However, these additional benefits are not officially recognized and therefore are not guaranteed.

Safety Profile

Acetylsalicyloyl Pentapeptide-33 is not a banned or regulated ingredient in cosmetics. However, like any other ingredient, it is essential to use it responsibly and in the right concentrations to ensure safety.

Generally, Acetylsalicyloyl Pentapeptide-33 is considered safe for use in cosmetics. It has a low allergenic potential, making it suitable for most skin types. However, individuals with sensitive skin or those who are allergic to acetylsalicylic acid may experience irritation or allergic reactions.

Potential side effects of topical application of Acetylsalicyloyl Pentapeptide-33 include:

  • Redness
  • Itching
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – there is currently insufficient data on the safety of topical use of Acetylsalicyloyl Pentapeptide-33 during pregnancy or breastfeeding. It is always advisable to consult a healthcare professional before using any new skincare product during these periods.

Adverse reactions to Acetylsalicyloyl Pentapeptide-33 are not common, but individual responses can vary. As with any new skincare product, it is recommended to perform a patch test before widespread usage to ensure there is no adverse reaction.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), and other various publicly available sources.