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Ingredient Analysis: Ascorbyl Tetraisopalmitate

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unlock the secrets of Ascorbyl Tetraisopalmitate (pronounced as-kor-bil tet-rai-so-pal-mi-tate), a potent Vitamin C derivative used in skincare. Discover its synthesis, benefits, uses, and safety profile in our comprehensive guide.

What is Ascorbyl Tetraisopalmitate?

Ascorbyl Tetraisopalmitate, also known as L-ascorbic acid, tetraisohexadecanoate, is a derivative of Vitamin C and is commonly used in the cosmetic industry. It is a fat-soluble compound, which means it can easily penetrate the skin’s lipid layer, making it an effective ingredient in skincare products. This ingredient is synthesized by combining ascorbic acid (Vitamin C) with isopalmitic acid, resulting in a stable and potent compound.

The use of Ascorbyl Tetraisopalmitate in cosmetics can be traced back to the increasing demand for antioxidants in skincare products. Antioxidants are known for their ability to neutralize harmful free radicals, which can cause skin damage and premature aging. Ascorbyl Tetraisopalmitate, being a derivative of Vitamin C, carries these antioxidant properties, making it a popular choice among cosmetic manufacturers.

Compared to other Vitamin C derivatives like Ascorbic Acid or Sodium Ascorbyl Phosphate, Ascorbyl Tetraisopalmitate is more stable and less likely to degrade in the presence of light and air. This stability makes it a more reliable ingredient in skincare formulations. However, it’s important to note that while all these derivatives carry the benefits of Vitamin C, their effectiveness and potency can vary.

Ascorbyl Tetraisopalmitate is typically used in a variety of skincare products, including moisturizers, serums, and anti-aging creams. Its emollient properties make it an excellent ingredient for products aimed at hydrating and softening the skin. Additionally, its antioxidant properties make it a valuable addition to products designed to protect the skin from environmental stressors.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Ascorbyl Tetraisopalmitate:

Antioxidant Properties

Ascorbyl Tetraisopalmitate is known for its powerful antioxidant properties. In simple terms, antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable molecules that the body produces as a reaction to environmental and other pressures. In the context of skincare, this means that Ascorbyl Tetraisopalmitate can help protect your skin from damage caused by exposure to harmful elements such as pollution and UV rays. This can result in a healthier and more youthful-looking complexion.

Emollient Benefits

Another official function of Ascorbyl Tetraisopalmitate is its role as an emollient. Emollients are substances that soften and moisturize the skin and decrease itching and flaking. They work by forming an oily layer on the top of the skin that traps water in the skin. When used in cosmetics, Ascorbyl Tetraisopalmitate can help to hydrate the skin, leaving it feeling soft and smooth. This can be particularly beneficial for those with dry or sensitive skin.

It’s important to note that these benefits are based on the officially recognized and defined functions of Ascorbyl Tetraisopalmitate. There may be other benefits and uses of this ingredient that go beyond these functions, but these are the primary benefits as recognized by the CosIng Database.

Safety Profile

Ascorbyl Tetraisopalmitate is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products, as per the CosIng Database, the Personal Care Products Council (PCPC), and the US Food & Drug Administration (FDA).

However, like any cosmetic ingredient, it has the potential to cause allergic reactions in some individuals. It is always recommended to perform a patch test before using any new product containing this ingredient to ensure you do not have an adverse reaction.

Potential side effects of topical application of Ascorbyl Tetraisopalmitate may include:

  • Redness
  • Itching
  • Swelling
  • Stinging or burning sensation

A note for women who are pregnant and/or breastfeeding – there is currently insufficient data on the safety of topical use of Ascorbyl Tetraisopalmitate during pregnancy or breastfeeding. Therefore, it is recommended to consult a healthcare professional for further advice.

Adverse reactions to Ascorbyl Tetraisopalmitate are not common, but they can occur. It is always recommended to perform a patch test before using any new product containing this ingredient to ensure you do not have an adverse reaction.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.