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Ingredient Analysis: Caffeoyl Hexapeptide-48

This page was last updated: 6 months ago. All information accurate at time of publishing.
Uncover the secrets of Caffeoyl Hexapeptide-48 (pronounced: kaf-ee-oyl hexa-peptide-48), a unique cosmetic ingredient with antioxidant and skin-protecting properties. Learn about its production, benefits, uses, and safety profile in this comprehensive guide.

What is Caffeoyl Hexapeptide-48?

Caffeoyl Hexapeptide-48 is a unique cosmetic ingredient that is derived from the reaction of Caffeic Acid and Hexapeptide-48. This compound is also known by its other names such as CAPE-48 and CH-48. It is a complex molecule that combines the antioxidant properties of caffeic acid, a plant-based compound, with the skin-enhancing benefits of hexapeptides.

The use of Caffeoyl Hexapeptide-48 in cosmetic products is a relatively recent development. Its introduction was driven by the ongoing search for effective antioxidants and skin protectants in the cosmetic industry. The combination of caffeic acid and hexapeptide-48 was found to offer a unique blend of properties that are beneficial for skin health and appearance.

The production of Caffeoyl Hexapeptide-48 involves a chemical reaction between caffeic acid and hexapeptide-48. This process results in a compound that harnesses the antioxidant power of caffeic acid and the skin-protecting capabilities of hexapeptides.

When compared to other cosmetic ingredients with similar functions, Caffeoyl Hexapeptide-48 stands out due to its dual action. While many ingredients offer either antioxidant or skin-protecting benefits, this compound provides both. This makes it a versatile ingredient that can enhance the efficacy of a wide range of cosmetic products.

Typically, Caffeoyl Hexapeptide-48 is used in products that are designed to protect and enhance the skin. These include moisturizers and serums, where it works to neutralize harmful free radicals and protect the skin from damage. Its unique properties make it a valuable addition to any skincare routine.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Caffeoyl Hexapeptide-48:

Antioxidant Properties

One of the primary benefits of Caffeoyl Hexapeptide-48 is its antioxidant properties. In simple terms, antioxidants are substances that help protect our skin cells from damage. They do this by neutralizing harmful molecules known as free radicals, which are produced in our skin as a result of exposure to environmental stressors like UV rays and pollution. By neutralizing these free radicals, Caffeoyl Hexapeptide-48 helps to prevent the oxidative stress that can lead to premature skin aging, including wrinkles and fine lines. This means that products containing this ingredient can help to keep your skin looking younger and healthier for longer.

Skin Protecting

Another key benefit of Caffeoyl Hexapeptide-48 is its skin-protecting function. This means that it helps to strengthen the skin’s natural barrier, which is responsible for keeping harmful substances out and locking moisture in. A strong skin barrier is essential for maintaining healthy, hydrated skin. By enhancing the skin’s barrier function, Caffeoyl Hexapeptide-48 can help to prevent dryness and dehydration, leaving the skin feeling soft, smooth, and supple. It can also help to protect the skin from environmental damage, further contributing to its anti-aging effects.

It’s important to note that these benefits are based on the officially recognized and defined functions of Caffeoyl Hexapeptide-48, as per the CosIng Database. There may be other benefits and uses of this ingredient that go beyond the scope of these official functions. However, these additional benefits are not officially recognized and therefore cannot be guaranteed.

Safety Profile

Caffeoyl Hexapeptide-48 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in skincare and cosmetic products. However, as with any ingredient, individual reactions can vary and it is always recommended to do a patch test before using a new product widely.

As for its allergenic potential, it is low. However, individuals with specific sensitivities or allergies should always check the ingredients of any product before use.

Potential side effects of topical application of Caffeoyl Hexapeptide-48 may include:

  • Minor skin irritation
  • Redness
  • Dryness

A note for women who are pregnant and/or breastfeeding – there is currently insufficient data on the safety of topically applied Caffeoyl Hexapeptide-48 during pregnancy or breastfeeding. Therefore, it is recommended to consult a healthcare professional for further advice.

Side effects or adverse reactions from this ingredient are not common. However, as mentioned earlier, it is always recommended to conduct a patch test before widespread usage to ensure there is no adverse reaction.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.