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Ingredient Analysis: Caffeoyl Tetrapeptide-19 Caffeamide

This page was last updated: 6 months ago. All information accurate at time of publishing.
Dive into the world of Caffeoyl Tetrapeptide-19 Caffeamide (pronounced: kaf-ee-oyl tet-ra-pep-tide-19 kaf-ee-amide), a unique cosmetic ingredient with antioxidant and skin-protecting properties. Discover its creation process, benefits, uses, and safety profile in this comprehensive guide.

What is Caffeoyl Tetrapeptide-19 Caffeamide?

Caffeoyl Tetrapeptide-19 Caffeamide is a unique cosmetic ingredient that is derived from Tetrapeptide-19, a peptide sequence of four amino acids. This derivative is created by modifying the N-terminus and the lysine residue with Caffeic Acid, a potent antioxidant found in many plants and fruits. This modification enhances the properties of the original peptide, making it a valuable addition to various skincare products.

The use of Caffeoyl Tetrapeptide-19 Caffeamide in cosmetic products is a relatively recent development. As the beauty industry continues to explore the potential benefits of peptides and antioxidants, this ingredient has emerged as a promising compound. Its unique structure, which combines the skin-nourishing properties of peptides with the antioxidant power of Caffeic Acid, sets it apart from other similar ingredients.

The process of making Caffeoyl Tetrapeptide-19 Caffeamide involves a series of chemical reactions. First, Tetrapeptide-19 is synthesized, usually through a process known as solid-phase peptide synthesis. Then, the peptide is modified by adding Caffeic Acid to the N-terminus and the lysine residue. This results in the formation of Caffeoyl Tetrapeptide-19 Caffeamide.

When compared to other cosmetic ingredients with similar functions, Caffeoyl Tetrapeptide-19 Caffeamide stands out due to its dual-action nature. While many ingredients offer either antioxidant or skin-protecting benefits, this compound provides both. Moreover, it also has chelating properties, which means it can bind to metal ions, preventing them from contributing to oxidative stress and skin damage.

Caffeoyl Tetrapeptide-19 Caffeamide is typically used in a variety of skincare products, including moisturizers and serums. Its antioxidant, chelating, and skin-protecting properties make it a versatile ingredient that can help to enhance the overall effectiveness of these products. Furthermore, its ability to act as a UV filter adds an additional layer of protection, making it an excellent choice for products designed to protect the skin from environmental stressors.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Caffeoyl Tetrapeptide-19 Caffeamide:

Antioxidant

As an antioxidant, Caffeoyl Tetrapeptide-19 Caffeamide helps to protect the skin from damage caused by harmful free radicals. These free radicals are often a result of environmental stressors such as pollution and UV radiation. By neutralizing these free radicals, this ingredient can help to maintain the health and vitality of the skin, reducing signs of aging such as wrinkles and fine lines.

Chelating

The chelating properties of Caffeoyl Tetrapeptide-19 Caffeamide mean that it can bind to metal ions, which can be harmful to the skin. By doing so, it prevents these ions from causing damage to the skin’s proteins and lipids, which can lead to premature aging and other skin issues. This makes it a valuable ingredient in skincare products designed to protect and preserve the skin.

Skin Protecting

Caffeoyl Tetrapeptide-19 Caffeamide also serves as a skin-protecting agent. This means it helps to maintain the skin’s barrier function, which is crucial for keeping out harmful substances and maintaining moisture levels. A strong skin barrier is essential for healthy, hydrated, and resilient skin.

UV Filter

Lastly, Caffeoyl Tetrapeptide-19 Caffeamide acts as a UV filter. It helps to absorb harmful UV rays, preventing them from penetrating the skin and causing damage. This can help to prevent sunburn, premature aging, and other forms of sun damage, making it a beneficial ingredient in sunscreens and other skincare products with SPF.

Please note that these benefits are based on the officially recognized functions of Caffeoyl Tetrapeptide-19 Caffeamide. There may be other benefits and uses that go beyond the scope of these official functions.

Safety Profile

Caffeoyl Tetrapeptide-19 Caffeamide is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, like any ingredient, it may not be suitable for everyone. Individuals with sensitive skin or those prone to allergic reactions should be cautious when using products containing this ingredient.

Potential side effects of topical application of Caffeoyl Tetrapeptide-19 Caffeamide may include:

  • Redness
  • Itching
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of topically applied Caffeoyl Tetrapeptide-19 Caffeamide during pregnancy or breastfeeding. As a result, it is recommended that you consult a healthcare professional for further advice if you are pregnant or breastfeeding and considering using products containing this ingredient.

Side effects or adverse reactions from Caffeoyl Tetrapeptide-19 Caffeamide are not common, but it is always recommended to perform a patch test before widespread usage to ensure no adverse reaction occurs.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.