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Ingredient Analysis: Caproyl Dipeptide-21 Amide

This page was last updated: 6 months ago. All information accurate at time of publishing.
Uncover the secrets of Caproyl Dipeptide-21 Amide (pronounced cap-royl di-pep-tide-21 a-mide), a synthetic ingredient revolutionizing the cosmetics industry with its antioxidant and skin-protecting properties; learn how it's made, what it does, and its safety profile in our comprehensive guide.

What is Caproyl Dipeptide-21 Amide?

Caproyl Dipeptide-21 Amide, also known as L-Glutamamide, N-(1-oxodecyl)-L-glutaminyl-, is a synthetic ingredient used in the formulation of a variety of cosmetic and personal care products. It is a dipeptide, which means it is composed of two amino acids, in this case, glutamic acid and glutamine. The ‘caproyl’ part of its name refers to the capric acid from which it is derived.

The use of Caproyl Dipeptide-21 Amide in cosmetics is a relatively recent development, with its antioxidant, skin conditioning, and skin protecting properties making it a valuable addition to many formulations. It is synthesized in the lab through a process that involves the reaction of the amino acids with capric acid, resulting in a compound that is both stable and effective.

While there are other dipeptides used in cosmetics, Caproyl Dipeptide-21 Amide stands out due to its unique combination of properties. Unlike some other dipeptides, it not only conditions and protects the skin but also acts as an antioxidant, helping to neutralize harmful free radicals that can cause damage to the skin.

Caproyl Dipeptide-21 Amide is typically used in products designed to nourish and protect the skin. This includes a wide range of products such as moisturizers, serums, and anti-aging treatments. Its versatility and effectiveness make it a popular choice for many cosmetic manufacturers.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Caproyl Dipeptide-21 Amide:

Antioxidant Properties

As an antioxidant, Caproyl Dipeptide-21 Amide plays a crucial role in protecting the skin from harmful free radicals. These free radicals are unstable molecules that can cause damage to the skin cells, leading to premature aging and other skin issues. By neutralizing these free radicals, Caproyl Dipeptide-21 Amide helps to maintain the health and vitality of the skin, keeping it looking youthful and radiant.

Skin Conditioning

Caproyl Dipeptide-21 Amide is also recognized for its skin conditioning properties. This means it helps to enhance the appearance and feel of the skin. It works by softening and smoothing the skin, reducing roughness, cracking, and irritation. This makes it an excellent ingredient for products aimed at improving skin texture and providing a more comfortable, pleasant skin feel.

Skin Protecting

Another key function of Caproyl Dipeptide-21 Amide is its skin-protecting abilities. It forms a protective barrier on the skin’s surface, helping to shield it from environmental stressors such as pollution and harsh weather conditions. This protective barrier also helps to lock in moisture, preventing the skin from drying out and maintaining its hydration levels.

It’s important to note that these benefits are based on the officially recognized and defined functions of Caproyl Dipeptide-21 Amide. There may be other benefits and uses that go beyond the scope of these official functions. However, as consumers, it’s crucial to be aware of the direct benefits this ingredient provides, so as not to be misled by brands and manufacturers.

Safety Profile

Caproyl Dipeptide-21 Amide is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, as with any ingredient, individual reactions can vary, and it may not be suitable for all skin types.

While it is not known to be a common allergen, there is always a potential for allergic reactions or skin irritation in some individuals. It is always recommended to perform a patch test before using a new product containing this ingredient widely on your skin.

  • Possible side effects of topical application of Caproyl Dipeptide-21 Amide may include skin irritation or redness.
  • In rare cases, it may cause a mild allergic reaction.

A note for women who are pregnant and/or breastfeeding – There is currently not enough data on the use of Caproyl Dipeptide-21 Amide during pregnancy or breastfeeding. As such, it is recommended to consult a healthcare professional before using products containing this ingredient during these periods.

Adverse reactions to Caproyl Dipeptide-21 Amide are not common, but it is always recommended to perform a patch test before using a new product containing this ingredient widely on your skin.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was performed by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.