What is Curcuminyl Glutaroyl Hexapeptide-8 Amide?
Curcuminyl Glutaroyl Hexapeptide-8 Amide, also known as CGH-8A, is a synthetic compound that is derived from curcumin, a natural ingredient found in turmeric. This compound is a combination of curcumin and a hexapeptide, which is a chain of six amino acids, linked together by a molecule of glutaric acid. The amide part of the name refers to the specific type of chemical bond that holds these components together.
The use of curcumin in cosmetics is a relatively recent development, with the first patents for its use in this context being filed in the early 2000s. The idea to combine curcumin with a hexapeptide and glutaric acid to create Curcuminyl Glutaroyl Hexapeptide-8 Amide came from the realization that curcumin alone was not very stable or easily absorbed by the skin, but when combined with these other ingredients, its effectiveness and stability were greatly improved.
The process of making Curcuminyl Glutaroyl Hexapeptide-8 Amide involves several steps. First, curcumin is extracted from turmeric using a solvent. Then, the curcumin is reacted with glutaric acid and a hexapeptide in a process known as peptide coupling. The resulting compound is then purified and tested for quality and purity before being used in cosmetic products.
While there are other ingredients that serve similar functions in cosmetics, such as other antioxidants and skin conditioners, Curcuminyl Glutaroyl Hexapeptide-8 Amide stands out because of its unique combination of components. The curcumin provides powerful antioxidant properties, while the hexapeptide and glutaric acid help to improve the skin’s texture and appearance.
Curcuminyl Glutaroyl Hexapeptide-8 Amide is typically used in a variety of cosmetic products, including moisturizers and serums. Its antioxidant properties make it particularly beneficial in anti-aging products, where it can help to protect the skin from damage caused by free radicals. Its skin conditioning and emollient properties also make it a good choice for products designed to hydrate and soften the skin.
Benefits and Uses
In this section, we will delve into the officially recognized benefits and uses of Curcuminyl Glutaroyl Hexapeptide-8 Amide:
Antioxidant Properties
As an antioxidant, Curcuminyl Glutaroyl Hexapeptide-8 Amide plays a crucial role in protecting the skin from harmful free radicals. These free radicals are unstable molecules that can cause damage to the skin cells, leading to premature aging and other skin issues. By neutralizing these free radicals, this ingredient helps to maintain the health and vitality of the skin, keeping it looking youthful and radiant.
Skin Conditioning
Curcuminyl Glutaroyl Hexapeptide-8 Amide also serves as a skin conditioner. This means it helps to make the skin feel smoother, softer, and more supple. It achieves this by enhancing the skin’s natural moisture factor, improving its texture and appearance. Whether you have dry, oily, or combination skin, this ingredient can help to balance your skin’s moisture levels and keep it feeling comfortable and well-nourished.
Emollient Properties
As an emollient, Curcuminyl Glutaroyl Hexapeptide-8 Amide works to soften and soothe the skin. It does this by forming a protective layer on the skin’s surface that helps to lock in moisture. This can be particularly beneficial for those with dry or sensitive skin, as it can help to prevent moisture loss and keep the skin hydrated and healthy.
Please note that the benefits listed above are based exclusively on the officially recognized and defined functions of Curcuminyl Glutaroyl Hexapeptide-8 Amide. There may be other potential benefits and uses that go beyond the scope of these official functions.
Safety Profile
Curcuminyl Glutaroyl Hexapeptide-8 Amide is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, as with any ingredient, individual reactions can vary.
As an organic compound, it has a low allergenic potential. However, individuals with sensitive skin or known allergies should always patch test a new product before applying it widely.
Potential side effects of topical application of Curcuminyl Glutaroyl Hexapeptide-8 Amide may include:
- Redness
- Itching
- Skin irritation
A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of topical use of Curcuminyl Glutaroyl Hexapeptide-8 Amide during pregnancy or breastfeeding. As such, it is recommended to consult a healthcare professional before using products containing this ingredient.
Adverse reactions to Curcuminyl Glutaroyl Hexapeptide-8 Amide are not common, but it is always recommended to patch test any new product before widespread use to ensure there is no adverse reaction.
This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources that include the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.
