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Ingredient Analysis: Decapeptide-6

This page was last updated: 6 months ago. All information accurate at time of publishing.
Dive into the world of Decapeptide-6 (pronounced: deca-peptide-six), a synthetic peptide revolutionizing the cosmetic industry; discover its unique creation process, its skin-protecting benefits, and its safety profile in our comprehensive guide.

What is Decapeptide-6?

Decapeptide-6, also known as Decapeptide-6 Palmitoyl, is a synthetic peptide that is commonly used in the cosmetic industry. It is a chain of ten amino acids, specifically aspartic acid, glutamic acid, leucine, lysine, and tyrosine. These amino acids are linked together in a specific sequence to form the peptide. The term ‘decapeptide’ refers to the fact that it is a peptide with ten linked amino acids.

The use of Decapeptide-6 in cosmetics is relatively recent, with its introduction being a result of advancements in the understanding of skin biology and the role of peptides in skin health. It is synthesized in laboratories using a process called solid-phase peptide synthesis (SPPS), which allows for the precise linking of the amino acids in the correct order.

Decapeptide-6 is similar to other peptides used in cosmetics, such as Matrixyl and Argireline, which also aim to provide skin benefits. However, the specific sequence of amino acids in Decapeptide-6 is unique, and this sequence is believed to be responsible for its specific benefits.

Decapeptide-6 is typically used in a variety of skincare products, including moisturizers, serums, and anti-aging creams. Its primary functions, as per the CosIng Database, are as an antioxidant and skin-protecting agent. This makes it a popular ingredient in products designed to protect the skin from environmental damage and to improve the appearance of aging skin.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Decapeptide-6:

Antioxidant Properties

Decapeptide-6, as an antioxidant, plays a crucial role in protecting the skin from harmful free radicals. Free radicals are unstable molecules that can cause damage to healthy cells, leading to premature aging and other skin issues. The antioxidant properties of Decapeptide-6 neutralize these free radicals, preventing them from causing harm to the skin cells. This means that products containing Decapeptide-6 can help maintain the skin’s youthful appearance and health.

Skin Protecting

Another official function of Decapeptide-6 is its skin-protecting capabilities. This means that it can help to strengthen the skin’s natural barrier, protecting it from environmental stressors such as pollution and UV rays. This can result in healthier, more resilient skin. Furthermore, by reinforcing the skin’s barrier, Decapeptide-6 can also help to lock in moisture, preventing dryness and dehydration, and promoting a plump, hydrated complexion.

It’s important to note that these benefits are based on the officially recognized functions of Decapeptide-6. There may be additional benefits and uses that go beyond the scope of these official functions. However, as consumers, it’s crucial to be aware of the direct benefits provided by this ingredient, so as not to be misled by brands and manufacturers.

Safety Profile

Decapeptide-6 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in skincare products. However, like any ingredient, it may not be suitable for all skin types and there is always a potential for allergic reactions. It is always recommended to do a patch test before using any new product on a larger area of skin.

Some potential side effects of topical application of Decapeptide-6 may include:

  • Redness
  • Itching
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of topical use of Decapeptide-6 during pregnancy or breastfeeding. As with any cosmetic ingredient, if you are pregnant or breastfeeding, it is recommended to consult a healthcare professional before using products containing Decapeptide-6.

Side effects or adverse reactions from Decapeptide-6 are not common, but they can occur. It is always recommended to do a patch test before using any new product on a larger area of skin.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.