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Ingredient Analysis: Dihydroxybenzylidine Thiazolidinedione

This page was last updated: 6 months ago. All information accurate at time of publishing.
Dive into the world of Dihydroxybenzylidine Thiazolidinedione (pronounced: Di-hydroxy-benzyl-idine Thia-zolidine-dione), a synthetic compound used in cosmetics, and discover its creation process, benefits, and safety profile in our comprehensive guide.

What is Dihydroxybenzylidine Thiazolidinedione?

Dihydroxybenzylidine Thiazolidinedione, also known as 2,4-Thiazolidinedione, 5-[(2,4-dihydroxyphenyl)methylene]-, (5Z)-, is a synthetic compound that is primarily used in the cosmetic industry. This ingredient is derived from a combination of organic compounds, including 2,4-dihydroxybenzaldehyde and thiazolidine-2,4-dione. The chemical structure of Dihydroxybenzylidine Thiazolidinedione is characterized by a thiazolidinedione ring, which is a heterocyclic compound with sulfur and nitrogen atoms, and a benzylidine group that contains two hydroxyl groups.

The use of Dihydroxybenzylidine Thiazolidinedione in cosmetics is relatively recent, with its antioxidant and skin-protecting properties being recognized and utilized in the last few decades. The production of Dihydroxybenzylidine Thiazolidinedione involves a series of chemical reactions, starting with the condensation of 2,4-dihydroxybenzaldehyde and thiazolidine-2,4-dione, followed by a series of purification processes to ensure the purity and safety of the final product.

While there are other antioxidants and skin-protecting ingredients used in cosmetics, such as vitamin C and E, Dihydroxybenzylidine Thiazolidinedione stands out due to its unique chemical structure. This structure allows it to effectively neutralize harmful free radicals and protect the skin from oxidative stress, which can lead to premature aging and skin damage.

Dihydroxybenzylidine Thiazolidinedione is typically used in a variety of cosmetic products, including moisturizers, serums, and anti-aging creams. Its potent antioxidant properties make it a valuable addition to these products, helping to enhance their skin-protecting and rejuvenating effects.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Dihydroxybenzylidine Thiazolidinedione:

Antioxidant Properties

Dihydroxybenzylidine Thiazolidinedione is officially recognized as an antioxidant. In the context of cosmetics, this means that it can help protect your skin from damage caused by harmful free radicals. Free radicals are unstable molecules that can cause damage to your skin cells, leading to premature aging and other skin issues. By neutralizing these free radicals, Dihydroxybenzylidine Thiazolidinedione can help maintain the health and appearance of your skin.

Skin Protecting

Another official function of Dihydroxybenzylidine Thiazolidinedione is its skin-protecting properties. This ingredient can form a protective barrier on the surface of your skin, helping to shield it from environmental stressors like pollution and UV rays. This can help prevent skin damage and keep your skin looking healthy and youthful.

It’s important to note that these benefits are based on the officially recognized and defined functions of Dihydroxybenzylidine Thiazolidinedione. There may be other benefits and uses of this ingredient that go beyond the scope of these official functions. However, these additional benefits are not officially recognized and should be considered with caution.

Safety Profile

Dihydroxybenzylidine Thiazolidinedione is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, like any ingredient, it may not be suitable for everyone and could potentially cause allergic reactions in some individuals.

Potential side effects of topical application of Dihydroxybenzylidine Thiazolidinedione may include:

  • Redness
  • Itching
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – There is a lack of data on the safety of topical usage of Dihydroxybenzylidine Thiazolidinedione during pregnancy or breastfeeding. Therefore, it is recommended to consult a healthcare professional for further advice before using products containing this ingredient.

Side effects or adverse reactions from Dihydroxybenzylidine Thiazolidinedione are not common, but it’s always a good idea to perform a patch test before using any new product widely. Apply a small amount of the product to a patch of skin on your inner forearm and wait 24 hours to see if any reaction occurs.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, whose sources include the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.