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Ingredient Analysis: Ethyl Nitrotrifluoromethylphenyl Citramalamide

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unravel the mystery of Ethyl Nitrotrifluoromethylphenyl Citramalamide (pronounced: Eth-yl Nitro-tri-fluoro-methyl-phenyl Citra-mala-mide), a potent anti-sebum ingredient in cosmetics, as we delve into its creation, benefits, and safety profile.

What is Ethyl Nitrotrifluoromethylphenyl Citramalamide?

Ethyl Nitrotrifluoromethylphenyl Citramalamide, also known as Butanoic acid, 3-hydroxy-3-methyl-4-[[4-nitro-3- (trifluoromethyl)phenyl]amino]-4-oxo-, ethyl ester,(3S)-, is a synthetic ingredient used in the cosmetics industry. This compound is a derivative of butanoic acid, a naturally occurring short-chain fatty acid, which is chemically modified to enhance its properties and effectiveness.

The use of Ethyl Nitrotrifluoromethylphenyl Citramalamide in cosmetics is relatively recent, with the ingredient gaining popularity due to its anti-sebum properties. It was developed in response to the need for effective ingredients that can control sebum production, a common concern in skincare, particularly for individuals with oily or acne-prone skin.

The production of Ethyl Nitrotrifluoromethylphenyl Citramalamide involves a series of chemical reactions. It starts with butanoic acid, which is then subjected to a series of modifications, including the introduction of a nitro group, a trifluoromethyl group, and an ethyl ester group. This results in a compound with enhanced sebum-controlling properties.

While there are other ingredients in the market that also exhibit anti-sebum properties, such as salicylic acid and niacinamide, Ethyl Nitrotrifluoromethylphenyl Citramalamide stands out due to its unique chemical structure. The presence of the nitro group and the trifluoromethyl group in its structure enhances its ability to control sebum production, making it a potent ingredient for this purpose.

Ethyl Nitrotrifluoromethylphenyl Citramalamide is typically used in products designed to control oil production and shine, such as mattifying moisturizers, oil-control serums, and acne treatments. Its potent anti-sebum properties make it a valuable ingredient in these types of products.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Ethyl Nitrotrifluoromethylphenyl Citramalamide:

Anti-Sebum

Ethyl Nitrotrifluoromethylphenyl Citramalamide is officially recognized for its anti-sebum function. In layman’s terms, this means that it helps control the production of sebum, the natural oil produced by your skin’s sebaceous glands. Sebum is necessary for keeping your skin hydrated and protected, but too much of it can lead to oily skin, clogged pores, and acne. By regulating sebum production, Ethyl Nitrotrifluoromethylphenyl Citramalamide can help maintain a healthy balance, preventing these issues and promoting clearer, healthier skin.

It’s important to note that this benefit is directly linked to the ingredient’s official function as defined by the CosIng Database. There may be other potential benefits and uses of Ethyl Nitrotrifluoromethylphenyl Citramalamide that go beyond this scope, but for the purpose of this article, we are focusing on its officially recognized function.

Safety Profile

As of the time of writing, Ethyl Nitrotrifluoromethylphenyl Citramalamide is not a banned or regulated ingredient in cosmetics. However, like any ingredient, it is essential to consider its safety, suitability, and allergenic potential.

While generally considered safe for topical use, Ethyl Nitrotrifluoromethylphenyl Citramalamide may cause some side effects. These may include:

  • Redness
  • Itching
  • Dryness
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – data/research on this particular ingredient’s topical usage during pregnancy is lacking. Therefore, it is recommended to consult a healthcare professional for further advice.

Side effects or adverse reactions from Ethyl Nitrotrifluoromethylphenyl Citramalamide are not common. However, as with any new skincare product, it is recommended to perform a patch test before widespread usage to ensure no adverse reaction occurs.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.