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Ingredient Analysis: Heptapeptide-49 SH-Decapeptide-8 SP

This page was last updated: 6 months ago. All information accurate at time of publishing.
Uncover the secrets of Heptapeptide-49 Sh-Decapeptide-8 Sp (pronounced hep-ta-pep-tide forty-nine sh-deca-pep-tide eight sp), a synthetic peptide revolutionizing skincare with its anti-sebum properties; learn how it's made, its benefits, and safety profile in this comprehensive guide.

What is Heptapeptide-49 Sh-Decapeptide-8 Sp?

Heptapeptide-49 Sh-Decapeptide-8 Sp, also known as Heptapeptide-49 and sh-Decapeptide-8 SP, is a synthetic peptide used in the cosmetic industry. This fusion peptide is composed of 17 amino acids, which may contain disulfide bonds and/or glycosylation, and is made up of the proper sequence of the 20 standard amino acids. It is a lab-created ingredient, synthesized for its specific properties and benefits in skincare products.

The use of peptides in cosmetics is a relatively recent development, with the first peptide-based products appearing on the market in the early 2000s. Since then, the use of peptides like Heptapeptide-49 Sh-Decapeptide-8 Sp has grown due to their potential benefits for skin health. The creation of this specific peptide involves a complex process of amino acid sequencing and peptide bonding, carried out in controlled laboratory conditions.

Heptapeptide-49 Sh-Decapeptide-8 Sp is similar to other peptides used in cosmetics in that it is designed to provide specific benefits to the skin. However, what sets it apart is its function as an anti-sebum agent. This means it can help to control oil production in the skin, making it particularly beneficial for those with oily or combination skin types.

Typically, you will find Heptapeptide-49 Sh-Decapeptide-8 Sp in products designed to control oil production and improve skin health. This includes products like moisturizers, serums, and other skincare items. Its unique properties make it a valuable addition to these products, helping to enhance their effectiveness and provide additional benefits to the user.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Heptapeptide-49 Sh-Decapeptide-8 Sp:

Anti-Sebum

Heptapeptide-49 Sh-Decapeptide-8 Sp is officially recognized for its anti-sebum properties. In layman’s terms, this means it helps control the production of sebum, the oily substance produced by our skin’s sebaceous glands. Excessive sebum production can lead to oily skin, clogged pores, and acne. By regulating sebum production, Heptapeptide-49 Sh-Decapeptide-8 Sp can help maintain a balanced and healthy skin condition, reducing the likelihood of skin issues related to excessive oiliness.

It’s important to note that the benefits listed here are based on the officially recognized and defined functions of Heptapeptide-49 Sh-Decapeptide-8 Sp. There may be other potential benefits and uses of this ingredient that go beyond the scope of its official functions. However, these additional benefits are not officially recognized and therefore, not discussed in this article.

Safety Profile

Heptapeptide-49 sh-Decapeptide-8 SP is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, like any ingredient, it may not be suitable for everyone and there is always a potential for allergic reactions.

Potential side effects of topical application of Heptapeptide-49 sh-Decapeptide-8 SP may include:

  • Redness
  • Itching
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of Heptapeptide-49 sh-Decapeptide-8 SP during pregnancy or breastfeeding. As such, it is recommended that you consult a healthcare professional for further advice before using products containing this ingredient.

Adverse reactions to Heptapeptide-49 sh-Decapeptide-8 SP are not common, but it is always recommended to perform a patch test before widespread usage to ensure you do not have an allergic reaction to this ingredient.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator, using a TiS-appointed industry consultant. The sources for this analysis include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.