What is Hexamidine Diisethionate?
Hexamidine Diisethionate, also known as 2-Hydroxyethanesulphonic acid, is a compound with 4,4′-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] (2:1). This synthetic ingredient is widely used in the cosmetic industry for its anti-seborrheic, antimicrobial, and preservative properties. It is also known by other names such as Hexamidine Diisethionate, Hexamidine Isethionate, and Hexamidine Isethionate.
The use of Hexamidine Diisethionate in cosmetic products dates back several decades. It was initially developed for its antimicrobial properties and was later found to be effective in controlling sebum production, making it a popular ingredient in anti-acne and anti-dandruff products. The ingredient is synthesized through a complex chemical process involving the reaction of hexamidine with 2-hydroxyethanesulphonic acid.
Hexamidine Diisethionate is often compared to other antimicrobial and anti-seborrheic ingredients such as Triclosan and Zinc Pyrithione. While these ingredients also offer antimicrobial and anti-seborrheic benefits, Hexamidine Diisethionate is often preferred for its additional preservative properties. This makes it a versatile ingredient that can perform multiple functions in a single product.
Hexamidine Diisethionate is typically used in a wide range of cosmetic products. Its anti-seborrheic properties make it a popular choice for products designed to control oil production, such as facial cleansers, toners, and moisturizers. Its antimicrobial and preservative properties also make it a common ingredient in products that need to have a long shelf life, such as serums, creams, and lotions.
Benefits and Uses
In this section, we will delve into the officially recognized benefits and uses of Hexamidine Diisethionate:
Anti-Seborrheic
Hexamidine Diisethionate is recognized for its anti-seborrheic properties. In simpler terms, it helps in controlling the production of sebum, an oily substance produced by our skin’s sebaceous glands. Excessive sebum can lead to oily skin and scalp, which in turn can cause various skin issues like acne, blackheads, and dandruff. By regulating sebum production, Hexamidine Diisethionate helps in maintaining a healthy balance of skin oils, thereby promoting clearer and healthier skin and scalp.
Antimicrobial
Another significant benefit of Hexamidine Diisethionate is its antimicrobial properties. This means it can inhibit the growth of microorganisms such as bacteria and fungi on the skin. This is particularly beneficial in preventing skin infections and promoting overall skin health. It’s also why this ingredient is commonly found in products like deodorants, body washes, and acne treatments, where its antimicrobial action can be most effective.
Preservative
Hexamidine Diisethionate also functions as a preservative in cosmetic products. Preservatives are crucial in preventing the growth of harmful bacteria, yeast, and mold in products, thereby extending their shelf life. This ensures that the product remains safe and effective to use for a longer period.
It’s important to note that these benefits are exclusively based on the officially recognized and defined functions of Hexamidine Diisethionate. There may be other benefits and uses of this ingredient that go beyond the scope of these official functions. However, as consumers, it’s essential to base our understanding and expectations on validated and officially recognized information to avoid being misled by brands and manufacturers.
Safety Profile
Hexamidine Diisethionate is not a banned or heavily regulated ingredient in cosmetics. However, like any ingredient, its use is subject to the general safety requirements of cosmetic products. It is generally considered safe for use in cosmetics, but as with any ingredient, individual reactions can vary.
As for its allergenic potential, Hexamidine Diisethionate is not commonly associated with allergic reactions. However, it’s always possible for an individual to have a unique sensitivity or allergy. Therefore, it’s always recommended to do a patch test before using a new product containing this ingredient.
Some potential side effects of topical application of Hexamidine Diisethionate include:
- Minor skin irritation
- Dryness
- Redness
A note for women who are pregnant and/or breastfeeding – there is currently not enough data to definitively state whether Hexamidine Diisethionate is safe for use during pregnancy or breastfeeding. As always, it’s best to consult a healthcare professional for advice on using any new products during this time.
Adverse reactions to Hexamidine Diisethionate are not common, but they can occur. It’s always a good idea to perform a patch test before using a product containing this ingredient on a larger area of skin.
This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was performed by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.
