What is Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8?
Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 is a synthetic fusion peptide, a type of ingredient that is becoming increasingly popular in the world of cosmetics. It is produced through a complex process of fermentation in E. coli, a type of bacteria. The starting gene for this ingredient is synthesized by fusing the gene from sh-Oligopeptide-75 and sh-Polypeptide-8 with the initiation code for methionine. This fusion peptide is composed of 225 amino acids, which may contain disulfide bonds and/or glycosylation, and consists of the proper sequence of the 20 standard amino acids.
The use of Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 in cosmetics is a relatively recent development. Its unique properties were discovered through extensive research and testing, leading to its incorporation in a variety of cosmetic products. The process of creating this ingredient involves a high level of precision and scientific knowledge, making it a testament to the advances in cosmetic science.
While there are other peptides used in cosmetics, Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 stands out due to its unique composition and the method of its production. It is a single chain synthetic fusion peptide, which sets it apart from other peptides that are often multi-chain. Furthermore, the use of E. coli for fermentation is a unique aspect of its production process.
Typically, Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 is found in a variety of skincare products, including moisturizers and serums. Its official functions, as per the CosIng Database, are as an antioxidant, skin conditioner, and skin protector. These properties make it a versatile ingredient that can contribute to the overall effectiveness of a cosmetic product.
Benefits and Uses
In this section, we will delve into the officially recognized benefits and uses of Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8:
Antioxidant Properties
As an antioxidant, Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 helps to protect the skin from damage caused by harmful free radicals. These free radicals are unstable molecules that can damage the skin cells, leading to premature aging and other skin issues. By neutralizing these free radicals, Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 helps to maintain the health and vitality of the skin.
Skin Conditioning
Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 also serves as a skin conditioner. This means it helps to make the skin feel smoother and softer by enhancing its water-retaining properties. This ingredient can help to improve the texture and appearance of the skin, making it look more youthful and radiant.
Skin Protecting
Another key function of Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 is its skin-protecting properties. It helps to form a barrier on the skin’s surface, which helps to protect it from environmental stressors such as pollution and UV rays. This can help to prevent skin damage and maintain the skin’s overall health and appearance.
It’s important to note that these benefits are based on the officially recognized and defined functions of Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8. There may be other benefits and uses of this ingredient that go beyond the scope of these official functions, but these are the primary benefits as recognized by the CosIng Database.
Safety Profile
Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 is not a banned or regulated ingredient in cosmetics. It is produced through a safe fermentation process and is generally considered safe for use in cosmetic products. However, as with any ingredient, individual reactions may vary and it is always recommended to perform a patch test before widespread usage.
As for its allergenic potential, it is low. However, individuals with a known allergy to any of the 20 standard amino acids present in this ingredient should avoid its use. The potential side effects of topical application of this ingredient include:
- Minor skin irritation
- Redness
- Dryness
A note for women who are pregnant and/or breastfeeding – While there is no specific data suggesting that Methionyl Sh-Oligopeptide-75 Sh-Polypeptide-8 is harmful during pregnancy or breastfeeding, there is also a lack of comprehensive studies on this topic. Therefore, it is always advisable to consult a healthcare professional before using any new skincare product during these periods.
Adverse reactions to this ingredient are not common, but they can occur. It is always recommended to perform a patch test before widespread usage to ensure no adverse reaction occurs.
This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.
