What is Nicotinoyl Pentapeptide-33?
Nicotinoyl Pentapeptide-33 is a synthetic compound derived from the reaction of Niacin, also known as Vitamin B3, and Pentapeptide-33. This unique compound is also known under the INCI name Nicotinoyl Tripeptide-1. The chemical composition of this ingredient includes a pentapeptide, which is a peptide consisting of five amino acids, and niacin, a nutrient that is essential for skin health.
The use of Nicotinoyl Pentapeptide-33 in cosmetic products is relatively recent, with the ingredient gaining popularity due to its antioxidant and skin-protecting properties. It is manufactured through a complex process that involves the synthesis of niacin and pentapeptide-33, resulting in a compound that is both stable and effective in skincare formulations.
While there are other ingredients that offer antioxidant and skin-protecting benefits, Nicotinoyl Pentapeptide-33 stands out due to its unique combination of niacin and a pentapeptide. This combination allows the ingredient to deliver the benefits of both components, offering a dual-action approach to skincare that is not commonly found in other ingredients.
Nicotinoyl Pentapeptide-33 is typically used in a variety of skincare products, including moisturizers and serums. Its antioxidant properties make it an excellent addition to products designed to protect the skin from environmental stressors, while its skin-protecting benefits make it a valuable ingredient in products aimed at improving skin health and appearance. As a versatile and effective ingredient, Nicotinoyl Pentapeptide-33 is a valuable addition to any skincare routine.
Benefits and Uses
In this section, we will delve into the officially recognized benefits and uses of Nicotinoyl Pentapeptide-33:
Antioxidant Properties
Nicotinoyl Pentapeptide-33 is officially recognized for its antioxidant properties. In layman’s terms, this means it can help protect your skin from damage caused by harmful molecules known as free radicals. These free radicals are often the result of environmental stressors like pollution and UV rays. By neutralizing these free radicals, Nicotinoyl Pentapeptide-33 can help prevent premature aging and maintain the health and vitality of your skin.
Skin Protecting
Another official function of Nicotinoyl Pentapeptide-33 is its ability to protect the skin. This ingredient forms a protective barrier on the skin’s surface, which helps to shield it from external factors that can cause damage, such as harsh weather conditions, pollutants, and harmful UV rays. This protective barrier also helps to lock in moisture, keeping the skin hydrated and supple.
It’s important to note that the benefits listed above are based on the officially recognized and defined functions of Nicotinoyl Pentapeptide-33. There may be other benefits and uses of this ingredient that go beyond the scope of these official functions. However, these additional benefits are not officially recognized and therefore, should be considered with caution.
Safety Profile
Nicotinoyl Pentapeptide-33 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in skincare and cosmetic products. However, as with any ingredient, individual reactions can vary and it is always recommended to do a patch test before using any new product widely.
As far as allergenic potential is concerned, there is no specific data suggesting that Nicotinoyl Pentapeptide-33 is a common allergen. However, individuals with sensitive skin or known allergies to niacin or peptides may want to exercise caution.
Potential side effects of topical application of Nicotinoyl Pentapeptide-33 may include:
- Redness
- Itching
- Skin irritation
A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of topical use of Nicotinoyl Pentapeptide-33 during pregnancy or breastfeeding. As such, it is recommended to consult with a healthcare professional before using products containing this ingredient during these periods.
Adverse reactions to Nicotinoyl Pentapeptide-33 are not common, but as with any ingredient, individual reactions can vary. It is always recommended to do a patch test before using any new product widely.
This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The information has been provided by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.
