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Ingredient Analysis: Nicotinoyl Tripeptide-1

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unlock the secrets of Nicotinoyl Tripeptide-1 (pronounced: Nee-co-tin-oyl Try-pep-tide-one), a potent skincare ingredient derived from Niacin and Tripeptide-1, as we delve into its creation, benefits, safety, and potential side effects in this comprehensive guide.

What is Nicotinoyl Tripeptide-1?

Nicotinoyl Tripeptide-1 is a powerful skincare ingredient that is derived from the reaction of Niacin, also known as Vitamin B3, with Tripeptide-1. This compound is also known by other names such as Niacinamide Tripeptide-1 and Niacinyl Tripeptide-1. The chemical composition of this ingredient is unique as it combines the benefits of Niacin, a potent antioxidant, with the skin-rejuvenating properties of Tripeptide-1.

The use of Nicotinoyl Tripeptide-1 in cosmetic products has its roots in the scientific discovery of the beneficial effects of Niacin and peptides on the skin. Over time, researchers found that combining these two ingredients resulted in a compound that had enhanced skin-protecting properties. The process of creating Nicotinoyl Tripeptide-1 involves a chemical reaction between Niacin and Tripeptide-1, resulting in a compound that is easily absorbed by the skin.

When compared to other similar ingredients used for the same purposes, Nicotinoyl Tripeptide-1 stands out due to its dual action. While many ingredients offer either antioxidant or skin-protecting benefits, Nicotinoyl Tripeptide-1 provides both. This makes it a valuable addition to many skincare products.

Typically, Nicotinoyl Tripeptide-1 is used in a variety of skincare products due to its versatile benefits. It can be found in moisturizers, serums, and anti-aging creams, where it works to protect the skin from oxidative stress, improve skin elasticity, and reduce the appearance of fine lines and wrinkles.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Nicotinoyl Tripeptide-1:

Antioxidant Properties

As an antioxidant, Nicotinoyl Tripeptide-1 plays a crucial role in protecting the skin from harmful free radicals. These free radicals are unstable molecules that can cause damage to the skin cells, leading to premature aging and other skin issues. By neutralizing these free radicals, Nicotinoyl Tripeptide-1 helps to maintain the health and vitality of the skin, keeping it looking youthful and radiant.

Chelating Abilities

Nicotinoyl Tripeptide-1 also functions as a chelating agent. In simple terms, it has the ability to bind to metal ions, which can be harmful to the skin. By doing so, it prevents these metals from causing damage to the skin cells. This is particularly beneficial in areas with hard water, as it can help to protect the skin from the potentially damaging effects of heavy metals found in the water.

Skin Protecting

Another key function of Nicotinoyl Tripeptide-1 is its skin-protecting properties. It helps to strengthen the skin’s natural barrier, which is essential for keeping out harmful environmental factors like pollutants and UV rays. By reinforcing this barrier, Nicotinoyl Tripeptide-1 helps to keep the skin healthy and resilient, reducing the risk of skin issues such as dryness, sensitivity, and irritation.

It’s important to note that these benefits are based on the officially recognized and defined functions of Nicotinoyl Tripeptide-1. There may be other potential benefits and uses of this ingredient that go beyond these functions, but further research is needed to confirm these.

Safety Profile

Nicotinoyl Tripeptide-1 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, as with any ingredient, individual reactions can vary, and it is always recommended to do a patch test before using a new product widely.

As for its allergenic potential, Nicotinoyl Tripeptide-1 is not known to be a common allergen. However, individuals with a known allergy to niacin or peptides should avoid products containing this ingredient.

Potential side effects of topical application of Nicotinoyl Tripeptide-1 may include:

  • Redness
  • Itching
  • Swelling

A note for women who are pregnant and/or breastfeeding – There is currently limited data on the safety of topical use of Nicotinoyl Tripeptide-1 during pregnancy or breastfeeding. As such, it is recommended to consult a healthcare professional before using products containing this ingredient.

Adverse reactions to Nicotinoyl Tripeptide-1 are not common, but as with any ingredient, individual reactions can vary. It is always recommended to do a patch test before using a new product widely.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), and other various publicly available sources.