What is Oligopeptide-158 Amide?
Oligopeptide-158 Amide is a synthetic peptide that is used in the cosmetic industry. It is composed of 12 amino acids, including glutamic acid, glycine, isoleucine, leucine, lysine, and serine. The C-terminus of the peptide is an amide, which is a key characteristic of its chemical structure. This ingredient does not have any other known names in the cosmetic industry.
The use of Oligopeptide-158 Amide in cosmetics is a relatively recent development. It was introduced as a result of ongoing research into the benefits of peptides for skin health. Peptides are short chains of amino acids, which are the building blocks of proteins such as collagen and elastin. These proteins are essential for maintaining the skin’s structure and elasticity. By incorporating peptides into cosmetic products, manufacturers aim to support the skin’s natural protein production and promote a healthier, more youthful appearance.
Oligopeptide-158 Amide is synthesized in the laboratory. The process involves combining the relevant amino acids in a specific sequence, then adding a compound to form the amide bond at the C-terminus. This results in a stable peptide that can be incorporated into various cosmetic formulations.
There are many other peptides used in cosmetics, but Oligopeptide-158 Amide stands out due to its specific function as an anti-sebum agent. Sebum is the oil produced by the skin’s sebaceous glands, and while it plays a crucial role in skin health, excessive sebum production can lead to issues such as oily skin and acne. Oligopeptide-158 Amide helps to regulate sebum production, making it a valuable ingredient in products designed for oily or acne-prone skin.
Typically, you can find Oligopeptide-158 Amide in products like moisturizers and serums. These products are designed to be absorbed into the skin, allowing the peptide to reach the deeper layers where it can exert its anti-sebum effects. By choosing products containing Oligopeptide-158 Amide, consumers can help to manage their skin’s oil production and promote a balanced, healthy complexion.
Benefits and Uses
In this section, we will delve into the officially recognized benefits and uses of Oligopeptide-158 Amide:
Anti-Sebum
Oligopeptide-158 Amide is officially recognized for its anti-sebum function. Sebum is a natural oil produced by our skin’s sebaceous glands. While it plays a crucial role in keeping our skin moisturized and protected, an overproduction can lead to oily skin, clogged pores, and acne breakouts. Oligopeptide-158 Amide helps to regulate this sebum production, ensuring a balanced and healthy skin environment. This makes it a valuable ingredient in products designed for oily or acne-prone skin. By controlling excess sebum, it can help to reduce shine, prevent clogged pores, and minimize the risk of acne breakouts.
It’s important to note that these benefits are directly linked to the officially recognized function of Oligopeptide-158 Amide. While there may be other potential benefits and uses, they go beyond the scope of the official functions and would require further research and validation.
Safety Profile
Oligopeptide-158 Amide is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, as with any ingredient, individual reactions may vary and it is always recommended to do a patch test before using a product containing this ingredient widely.
As a synthetic peptide, Oligopeptide-158 Amide is not known to have any allergenic potential. However, it is always possible for individuals to have unique sensitivities or allergies. If you experience any adverse reactions such as redness, itching, or swelling, discontinue use and consult a healthcare professional.
Potential side effects of topical application of Oligopeptide-158 Amide may include:
- Redness
- Itching
- Swelling
A note for women who are pregnant and/or breastfeeding – there is currently a lack of data on the safety of topical usage of Oligopeptide-158 Amide during pregnancy or breastfeeding. Therefore, it is recommended to consult a healthcare professional for further advice.
Adverse reactions to Oligopeptide-158 Amide are not common, but it is always recommended to do a patch test before widespread usage to ensure you do not have an individual sensitivity or allergy to this ingredient.
This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.
