What is R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2)?
R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) is a single chain fusion peptide that is used as an ingredient in cosmetic products. It is produced by fermentation in E. coli, a process that involves the fusion of the genes encoding for Oligopeptide-126, sh-Oligopeptide-1, sh-Polypeptide-124, and sh-Polypeptide-2. This fusion peptide consists of 193 amino acids, which may contain disulfide bonds and/or glycosylation, and is composed of the proper sequence of the 20 standard amino acids.
The use of this ingredient in cosmetics is relatively recent, with its development being driven by the increasing demand for products with antioxidant, skin conditioning, and emollient properties. The fusion of the four peptides results in a compound that is capable of delivering these benefits in a single ingredient, making it a valuable addition to many cosmetic formulations.
The production of R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) involves a complex process of gene synthesis and fermentation. The genes encoding for the four peptides are fused together and then inserted into E. coli for fermentation. The resulting fusion peptide is then harvested and purified for use in cosmetic products.
While there are other peptides used in cosmetics, R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) stands out due to its unique combination of peptides. This fusion results in a peptide with a unique amino acid sequence, which can deliver a range of benefits to the skin.
Typically, R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) is used in products designed to nourish and protect the skin, such as moisturizers and serums. Its antioxidant, skin conditioning, and emollient properties make it a versatile ingredient that can enhance the effectiveness of these products.
Benefits and Uses
In this section, we will delve into the officially recognized benefits and uses of R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2):
Antioxidant Properties
As an antioxidant, R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) plays a crucial role in protecting the skin from harmful free radicals. Free radicals are unstable molecules that can cause damage to the skin cells, leading to premature aging and other skin issues. By neutralizing these free radicals, this ingredient helps to maintain the health and vitality of the skin, keeping it looking youthful and radiant.
Skin Conditioning
Another key function of R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) is its ability to condition the skin. As a skin conditioner, it works by softening and smoothing the skin, enhancing its texture and appearance. This makes the skin feel more comfortable and look more attractive, contributing to an overall improved skin quality.
Emollient
As an emollient, R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) has the ability to moisturize and hydrate the skin. It does this by forming a protective layer on the skin’s surface, which helps to lock in moisture and prevent water loss. This results in a softer, smoother, and more hydrated skin, which is less prone to dryness and flaking.
It’s important to note that these benefits are based on the officially recognized and defined functions of R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2). There may be other potential benefits and uses of this ingredient that go beyond the scope of these official functions.
Safety Profile
R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, as with any ingredient, individual reactions can vary, and it is always recommended to perform a patch test before using a new product.
As for its allergenic potential, it is generally considered to have a low risk of causing allergic reactions. However, individuals with sensitive skin or known allergies to peptides should exercise caution.
Potential side effects of topical application of this ingredient may include:
- Redness
- Itching
- Skin irritation
A note for women who are pregnant and/or breastfeeding – there is currently insufficient data on the safety of R-(Oligopeptide-126 Sh-Oligopeptide-1 Sh-Polypeptide-124 Sh-Polypeptide-2) during pregnancy or breastfeeding. As such, it is recommended to consult a healthcare professional before using products containing this ingredient.
Side effects or adverse reactions from this ingredient are not common, but it is always recommended to perform a patch test before widespread usage to ensure no adverse reaction occurs.
This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.
