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Ingredient Analysis: R-Salmon Oligopeptide-1

This page was last updated: 6 months ago. All information accurate at time of publishing.
Discover the science behind R-Salmon Oligopeptide-1 (pronounced R-Salmon Oligo-peptide-one), a unique bioengineered skincare ingredient derived from salmon, its antioxidant and skin-protecting benefits, and its safety profile in our comprehensive guide.

What is R-Salmon Oligopeptide-1?

R-Salmon Oligopeptide-1, also known as Protamine, is a single-chain recombinant salmon protein that is used in the cosmetic industry for its skin-protecting and antioxidant properties. This unique ingredient is derived from the salmon species Oncorhynchus kisutch. The protein fragment of R-Salmon Oligopeptide-1 consists of 14 amino acids, which are arranged in the correct sequence of the 20 standard amino acids.

The use of R-Salmon Oligopeptide-1 in cosmetics is a relatively recent development, with the ingredient being produced through a sophisticated process of genetic engineering. The starting gene, a synthesized copy of a gene from the salmon, is introduced into E. coli bacteria. The bacteria then undergo fermentation, producing the R-Salmon Oligopeptide-1 protein.

While there are other skin-protecting and antioxidant ingredients available in the market, R-Salmon Oligopeptide-1 stands out due to its unique source and production process. Unlike many cosmetic ingredients that are derived from plants or synthetically produced in labs, R-Salmon Oligopeptide-1 is a product of bioengineering, making it a unique addition to the world of cosmetics.

Typically, R-Salmon Oligopeptide-1 is used in products that are designed to protect and nourish the skin. This includes a range of moisturizers and serums, where the ingredient can deliver its antioxidant benefits directly to the skin. Its unique properties make it a valuable addition to any skincare routine, offering protection against environmental stressors while also helping to maintain the skin’s natural balance.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of R-Salmon Oligopeptide-1:

Antioxidant Properties

One of the primary benefits of R-Salmon Oligopeptide-1 is its antioxidant properties. In simple terms, antioxidants are substances that help protect our skin cells from damage. They do this by neutralizing harmful molecules known as free radicals, which can be produced by things like pollution, sunlight, and even our own bodies. By neutralizing these free radicals, antioxidants like R-Salmon Oligopeptide-1 can help to maintain the health and vitality of our skin, potentially reducing signs of aging and giving the skin a more youthful appearance.

Skin Protecting

Another key benefit of R-Salmon Oligopeptide-1 is its skin-protecting function. This means that it can help to shield the skin from various forms of damage, such as environmental stressors like UV radiation and pollution. By providing this protective barrier, R-Salmon Oligopeptide-1 can help to maintain the skin’s overall health and integrity, potentially reducing the risk of skin problems and keeping the skin looking its best.

It’s important to note that these benefits are based on the officially recognized and defined functions of R-Salmon Oligopeptide-1. There may be other potential benefits and uses of this ingredient that go beyond these official functions, but these would require further research and are beyond the scope of this article.

Safety Profile

R-Salmon Oligopeptide-1 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in skincare products. However, like any ingredient, it may not be suitable for everyone. It’s always recommended to do a patch test before using a new product containing this ingredient to ensure you don’t have an allergic reaction.

While R-Salmon Oligopeptide-1 is generally well-tolerated, potential side effects of topical application may include:

  • Redness
  • Itching
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – there is currently limited data on the safety of topically applied R-Salmon Oligopeptide-1 during pregnancy or breastfeeding. As such, it’s recommended to consult a healthcare professional for further advice.

Adverse reactions to R-Salmon Oligopeptide-1 are not common, but they can occur. As with any new skincare product, it’s recommended to do a patch test before using it widely on your skin.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), and various other publicly available sources.