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Ingredient Analysis: S-Centipede Oligopeptide-1 Amide

This page was last updated: 5 months ago. All information accurate at time of publishing.
Unlock the secrets of S-Centipede Oligopeptide-1 Amide (pronounced S-Centipede Oligo-peptide-One Amide), a unique synthetic peptide with antimicrobial properties, derived from centipede protein, and discover its production, benefits, uses, and safety profile in our comprehensive guide.

What is S-Centipede Oligopeptide-1 Amide?

S-Centipede Oligopeptide-1 Amide, also known as Scolopendrasin-I, is a synthetic peptide derived from the protein found in the centipede species, Scolopendra subspinipes mutilans. This unique ingredient is a single chain centipede protein, which is synthesized to be identical to a portion of the Scolopendrasin-I protein. It is composed of 14 amino acids, with the C-terminus being an amide. The original protein in the centipede contains up to 45 amino acids, which are arranged in the correct sequence of the 20 standard amino acids.

The use of S-Centipede Oligopeptide-1 Amide in cosmetics is a relatively recent development. The potential of this ingredient was discovered through scientific research into the properties of centipede proteins. The synthetic version of this peptide was developed to harness these properties for cosmetic applications, while avoiding the ethical and practical issues associated with sourcing the protein directly from centipedes.

The production of S-Centipede Oligopeptide-1 Amide involves a complex process of protein synthesis. The desired sequence of amino acids is assembled in the laboratory, using advanced techniques to ensure that the synthetic peptide is identical to the portion of the Scolopendrasin-I protein that it is designed to mimic.

While there are many peptides used in cosmetics for their skin conditioning and protective properties, S-Centipede Oligopeptide-1 Amide stands out for its antimicrobial function. This makes it a valuable ingredient in products designed to protect the skin from harmful bacteria and other microorganisms.

S-Centipede Oligopeptide-1 Amide is typically used in a variety of cosmetic products, including moisturizers and serums. Its unique properties make it a versatile ingredient that can enhance the performance of these products, contributing to their ability to condition, protect, and improve the health of the skin.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of S-Centipede Oligopeptide-1 Amide:

Antimicrobial Properties

S-Centipede Oligopeptide-1 Amide has been officially recognized for its antimicrobial properties. In layman’s terms, this means it can help to kill or inhibit the growth of microorganisms on your skin. This can be particularly beneficial in skincare products, as it can help to prevent the growth of bacteria that can lead to skin infections and breakouts. It’s like having a tiny, invisible army on your skin, constantly fighting off harmful invaders.

Skin Conditioning

Another key benefit of S-Centipede Oligopeptide-1 Amide is its skin conditioning properties. This essentially means that it helps to soften and smooth your skin. It achieves this by enhancing the appearance and feel of dry or damaged skin by reducing flaking and restoring suppleness. So, if your skin is feeling a little rough or dry, this ingredient could help to make it feel soft and smooth again.

Skin Protecting

Finally, S-Centipede Oligopeptide-1 Amide is also recognized for its skin protecting properties. This means it can help to form a barrier on your skin’s surface, protecting it from environmental stressors like pollution and harsh weather conditions. This can help to prevent damage to your skin and keep it looking healthy and youthful.

It’s important to note that these benefits are based on the officially recognized and defined functions of S-Centipede Oligopeptide-1 Amide. There may be other benefits and uses that go beyond the scope of these official functions. However, these are the direct benefits that you can expect from this ingredient based on its defined functions.

Safety Profile

S-Centipede Oligopeptide-1 Amide is not a banned or regulated ingredient in cosmetics. It is synthetically produced to mimic a portion of the protein found in the centipede, Scolopendra subspinipes mutilans, and is considered safe for use in cosmetic products.

As for its allergenic potential, there is currently no evidence to suggest that S-Centipede Oligopeptide-1 Amide is a common allergen. However, as with any cosmetic ingredient, individual reactions can vary and it is always recommended to perform a patch test before widespread use.

Potential side effects of topical application of S-Centipede Oligopeptide-1 Amide may include:

  • Redness
  • Itching
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of topical use of products containing S-Centipede Oligopeptide-1 Amide during pregnancy or breastfeeding. As such, it is recommended to consult a healthcare professional for further advice.

Adverse reactions to S-Centipede Oligopeptide-1 Amide are not common, but as with any cosmetic ingredient, individual reactions can vary. It is always recommended to perform a patch test before widespread use.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources that include the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.