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Ingredient Analysis: SH-Polypeptide-64

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unravel the mysteries of Sh-Polypeptide-64 (pronounced as S-H-Poly-peptide-64), a bioengineered skincare ingredient, as we delve into its creation, benefits, and safety profile in this comprehensive guide.

What is Sh-Polypeptide-64?

Sh-Polypeptide-64, also known as AQP-1, is a synthetic ingredient used in the cosmetic industry for its antioxidant, skin conditioning, and skin protecting properties. It is a type of polypeptide, which are chains of amino acids, the building blocks of proteins. Specifically, Sh-Polypeptide-64 is a single-chain polypeptide that is bioengineered in laboratories.

The use of Sh-Polypeptide-64 in cosmetics is relatively recent, and it is part of a larger trend of incorporating scientifically advanced ingredients into skincare products. The ingredient is produced through a process known as recombinant DNA technology, where specific genes are inserted into bacteria, causing them to produce the desired polypeptide.

While there are other polypeptides used in cosmetics, Sh-Polypeptide-64 stands out for its specific functions. Unlike many other ingredients that serve a single purpose, Sh-Polypeptide-64 is a multitasker, providing antioxidant benefits, conditioning the skin, and offering protection from environmental stressors.

Sh-Polypeptide-64 is typically found in a variety of skincare products, including moisturizers and serums. Its versatility and beneficial properties make it a popular choice for brands seeking to enhance the effectiveness of their products.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Sh-Polypeptide-64:

Antioxidant

As an antioxidant, Sh-Polypeptide-64 helps to protect the skin from damage caused by harmful free radicals. These free radicals are unstable molecules that can damage the cells in your skin, leading to premature aging and skin diseases. By neutralizing these free radicals, Sh-Polypeptide-64 helps to maintain the health and vitality of your skin.

Skin Conditioning

Sh-Polypeptide-64 also functions as a skin conditioner. This means it helps to make the skin feel softer and smoother by enhancing its water retention capabilities. It does this by forming a barrier on the skin’s surface, which reduces the amount of water lost through the skin. This leads to improved skin texture and a more youthful appearance.

Skin Protecting

Another key function of Sh-Polypeptide-64 is its ability to protect the skin. It does this by forming a protective barrier on the skin’s surface, which helps to shield it from environmental stressors like UV rays and pollution. This protective barrier also helps to prevent moisture loss, keeping the skin hydrated and healthy.

It’s important to note that these benefits are based on the officially recognized and defined functions of Sh-Polypeptide-64. There may be other benefits and uses for this ingredient that go beyond these official functions, but these are the primary benefits as recognized by the CosIng Database.

Safety Profile

Sh-Polypeptide-64, also known as AQP-1, is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in skincare and cosmetic products. However, as with any ingredient, individual reactions can vary, and it may not be suitable for all skin types.

While Sh-Polypeptide-64 is not typically associated with allergenic potential, it is always recommended to perform a patch test before using any new product extensively. This can help identify any potential adverse reactions in a controlled manner.

Potential side effects of topical application of Sh-Polypeptide-64 may include:

  • Minor skin irritation
  • Redness
  • Dryness

A note for women who are pregnant and/or breastfeeding – While there is no specific data suggesting that Sh-Polypeptide-64 is harmful during pregnancy or breastfeeding, there is also a lack of extensive research in this area. Therefore, it is always recommended to consult a healthcare professional before using any new skincare or cosmetic products during these periods.

Adverse reactions to Sh-Polypeptide-64 are not common, but as mentioned earlier, individual responses can vary. Therefore, patch testing is always a good practice before widespread usage.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.