What is Tetrapeptide-33?
Tetrapeptide-33 is a synthetic peptide, a compound made up of a chain of amino acids. Specifically, it consists of four amino acids: arginine, phenylalanine, serine, and tyrosine. These amino acids are linked together in a specific sequence to form the tetrapeptide. This ingredient doesn’t have any other common names and is typically listed as Tetrapeptide-33 on cosmetic product labels.
The use of peptides in skincare products has a relatively recent history, with the first peptide-based products appearing in the early 2000s. Tetrapeptide-33 is one of the many peptides that have been synthesized for use in cosmetics, and it was developed with the aim of providing antioxidant and skin conditioning benefits.
The production of Tetrapeptide-33 involves a process known as peptide synthesis. This is a chemical process where the amino acids are linked together in a specific sequence. The process requires a high degree of precision and control to ensure the correct sequence is achieved.
There are many other peptides used in skincare products, such as Matrixyl (palmitoyl pentapeptide-4) and Argireline (acetyl hexapeptide-8). These peptides also offer skin conditioning benefits, but they differ in their specific amino acid sequences and therefore their exact effects on the skin. Unlike these peptides, Tetrapeptide-33 also has antioxidant properties, which can help to protect the skin from damage caused by free radicals.
Tetrapeptide-33 is typically used in a variety of skincare products, including moisturizers and serums. Its skin conditioning properties make it a valuable ingredient in products designed to improve the texture and appearance of the skin, while its antioxidant properties make it a useful addition to products aimed at protecting the skin from environmental damage.
Benefits and Uses
In this section, we will delve into the officially recognized benefits and uses of Tetrapeptide-33:
Antioxidant Properties
One of the primary benefits of Tetrapeptide-33 is its antioxidant properties. In layman’s terms, antioxidants are substances that help protect our skin cells from damage. They do this by neutralizing harmful molecules known as free radicals, which are produced in our bodies as a result of exposure to environmental stressors like pollution and UV radiation. By neutralizing these free radicals, Tetrapeptide-33 helps to prevent premature skin aging and maintain the overall health of your skin.
Skin Conditioning
Another key function of Tetrapeptide-33 is its skin conditioning properties. This means that it helps to make the skin feel smoother, softer, and more supple. It achieves this by enhancing the skin’s natural moisture retention capabilities, thereby preventing dryness and flakiness. This makes Tetrapeptide-33 a valuable ingredient in a variety of skincare products, including moisturizers, serums, and anti-aging creams.
It’s important to note that the benefits listed above are based on the officially recognized and defined functions of Tetrapeptide-33. There may be other potential benefits and uses of this ingredient that go beyond the scope of its official functions. However, further research is needed to fully understand and validate these potential benefits.
Safety Profile
Tetrapeptide-33 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in skincare and cosmetic products. However, like any ingredient, it may not be suitable for all skin types and there is always a potential for allergic reactions.
Some potential side effects of topical application of Tetrapeptide-33 include:
- Redness
- Itching
- Swelling
- Skin irritation
A note for women who are pregnant and/or breastfeeding – There is currently a lack of data regarding the safety of topically applied Tetrapeptide-33 during pregnancy or breastfeeding. As such, it is recommended to consult a healthcare professional for further advice.
Side effects or adverse reactions from Tetrapeptide-33 are not common, but it is always recommended to perform a patch test before widespread usage to ensure there is no adverse reaction.
This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was performed by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.
