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Ingredient Analysis: Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 SH-Polypeptide-80

This page was last updated: 5 months ago. All information accurate at time of publishing.
Unravel the mystery of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 (THDDO) - its creation, benefits, and safety profile in skincare products, all in this comprehensive guide.

What is Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80?

Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80, also known as THDDO, is a unique synthetic fusion peptide. It is a single chain peptide that is produced by the fermentation process in E. coli. The starting gene is synthesized by the fusion of the gene from Tetrapeptide-38, Hexapeptide-40, Decapeptide-27, Oligopeptide-91, Dipeptide-19, and sh-Polypeptide-80. This fused peptide contains 241 amino acids and consists of the proper sequence of the 20 standard amino acids.

The use of THDDO in cosmetic products is relatively recent, with the ingredient gaining popularity due to its antioxidant and skin conditioning properties. The fusion of multiple peptides into a single chain allows for a more potent and effective ingredient, providing multiple benefits to the skin.

THDDO is produced through a complex process of gene fusion and fermentation. The genes from Tetrapeptide-38, Hexapeptide-40, Decapeptide-27, Oligopeptide-91, Dipeptide-19, and sh-Polypeptide-80 are fused together to create a single gene. This gene is then inserted into E. coli bacteria, which are fermented to produce the peptide.

While there are other peptides used in cosmetic products, THDDO is unique due to its fusion of multiple peptides. This allows for a wider range of benefits and effects, making it a versatile ingredient in skincare products. However, like all ingredients, its effectiveness can vary depending on the formulation and concentration used in the product.

Typically, THDDO is used in a variety of skincare products, including moisturizers and serums. Its antioxidant properties help to protect the skin from environmental damage, while its skin conditioning effects help to improve the texture and appearance of the skin. It is a versatile ingredient that can be used in a wide range of products to provide multiple benefits to the skin.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80:

Antioxidant Properties

One of the primary benefits of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 is its antioxidant properties. Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable molecules that the body produces as a reaction to environmental and other pressures. In the context of skincare, this means that this ingredient can help protect your skin from the damaging effects of environmental stressors like pollution and UV rays. This can result in healthier, more youthful-looking skin.

Skin Conditioning

Another key benefit of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 is its skin conditioning properties. As a skin conditioner, this ingredient works to enhance the appearance and feel of skin by increasing its hydration, suppleness, and smoothness. It can help to improve the texture of your skin, making it feel softer and smoother to the touch. This can contribute to an overall improved complexion and healthier-looking skin.

It’s important to note that these benefits are based on the officially recognized and defined functions of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80. There may be other benefits and uses that go beyond the scope of these official functions, but these are the primary benefits you can expect from this ingredient in your skincare products.

Safety Profile

Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, like any ingredient, it may not be suitable for all skin types and there is always a potential for allergic reactions.

Potential side effects of topical application of this ingredient may include:

  • Redness
  • Itching
  • Dryness
  • Sensitivity

A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of topical use of Tetrapeptide-38 Hexapeptide-40 Decapeptide-27 Oligopeptide-91 Dipeptide-19 Sh-Polypeptide-80 during pregnancy or breastfeeding. It is recommended to consult a healthcare professional for further advice.

Side effects or adverse reactions from this ingredient are not common, but individual reactions can vary. It is always recommended to perform a patch test before using any new product widely on your skin.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.