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Ingredient Analysis: Tocophereth-18

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unravel the mystery of Tocophereth-18 (pronounced toh-koh-fair-eth-18), a synthetic derivative of Vitamin E, as we delve into its creation, benefits, uses, and safety in cosmetics.

What is Tocophereth-18?

Tocophereth-18, also known as 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol, ethoxylated (18 mol EO average molar ratio), is a synthetic ingredient derived from Tocopherol, commonly known as Vitamin E. This compound is created by ethoxylation, a chemical process in which ethylene oxide is introduced to Tocopherol, resulting in an ethoxylated derivative. The number 18 in its name signifies the average molar ratio of ethylene oxide in the compound.

The use of Tocophereth-18 in cosmetic products dates back several decades, as manufacturers sought to harness the beneficial properties of Vitamin E in a more stable and versatile form. Tocophereth-18 was found to be an effective solution, offering similar benefits to its parent compound while also demonstrating improved solubility and compatibility with a wider range of cosmetic formulations.

While Tocophereth-18 shares many similarities with other ethoxylated compounds, it is distinguished by its unique chemical structure, which includes a high concentration of methyl groups. This contributes to its antioxidant properties, making it particularly effective in protecting the skin from oxidative stress and environmental damage.

Typically, Tocophereth-18 is used in a variety of cosmetic and personal care products, including moisturizers, serums, cleansers, and anti-aging treatments. Its versatile nature allows it to serve multiple functions, acting as an antioxidant, skin conditioner, and cleansing agent. This makes it a valuable addition to many formulations, contributing to both the performance and aesthetic appeal of the final product.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Tocophereth-18:

Antioxidant Properties

Tocophereth-18 is officially recognized as an antioxidant. In the context of cosmetics, this means that it helps to protect your skin from damage caused by harmful free radicals. Free radicals are unstable molecules that can cause damage to your skin cells, leading to premature aging and other skin problems. By neutralizing these free radicals, Tocophereth-18 helps to maintain the health and vitality of your skin.

Skin Conditioning

Another official function of Tocophereth-18 is skin conditioning. This means that it helps to make your skin feel softer and smoother. It does this by increasing the water content of the top layers of your skin, which helps to improve its texture and appearance. This makes Tocophereth-18 a valuable ingredient in products designed to moisturize and nourish the skin.

Cleansing

Tocophereth-18 also has cleansing properties. It can help to remove dirt, oil, and other impurities from your skin, leaving it clean and refreshed. This makes it a useful ingredient in products like facial cleansers and body washes.

Please note that these benefits are based on the officially recognized and defined functions of Tocophereth-18. There may be other benefits and uses that go beyond the scope of these official functions. However, it’s important to remember that the effectiveness of Tocophereth-18, like any cosmetic ingredient, can vary depending on factors such as the concentration used in a product and how it is used.

Safety Profile

Tocophereth-18 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, like any ingredient, it may not be suitable for everyone and could potentially cause allergic reactions in some individuals.

Potential side effects of topical application of Tocophereth-18 include:

  • Redness
  • Itching
  • Burning sensation
  • Skin irritation

A note for women who are pregnant and/or breastfeeding – There is currently insufficient data on the safety of topically applied Tocophereth-18 during pregnancy or breastfeeding. It is always recommended to consult a healthcare professional for further advice.

Adverse reactions to Tocophereth-18 are not common, but they can occur. It is always recommended to perform a patch test before using any new product containing this ingredient to ensure you do not have an adverse reaction.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant whose sources include CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.