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Ingredient Analysis: Tocophereth-5

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unlock the secrets of Tocophereth-5 (pronounced toh-co-fair-eth-five), a synthetic ingredient derived from Vitamin E, as we delve into its creation, uses, benefits, and safety in cosmetics - all in one comprehensive guide.

What is Tocophereth-5?

Tocophereth-5, also known as 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol, ethoxylated (5 mol EO average molar ratio), is a synthetic ingredient derived from Tocopherol, commonly known as Vitamin E. It is a complex organic compound with a unique chemical structure that includes an ethoxylated benzopyran ring and a trimethyltridecyl side chain.

The use of Tocophereth-5 in cosmetics can be traced back to the industry’s constant search for effective antioxidants and skin conditioning agents. Recognizing the beneficial properties of Vitamin E, scientists developed a way to modify it to enhance its stability and effectiveness, resulting in the creation of Tocophereth-5.

The production of Tocophereth-5 involves a process known as ethoxylation, where Tocopherol is reacted with ethylene oxide under controlled conditions. This process increases the molecule’s size and alters its properties, making it more soluble in water and enhancing its ability to condition and cleanse the skin.

While Tocophereth-5 shares similarities with other ethoxylated ingredients, such as Tocophereth-50, it differs in the degree of ethoxylation. The number following ‘Tocophereth’ indicates the average number of ethylene oxide units in the molecule. Therefore, Tocophereth-5 has fewer ethylene oxide units compared to Tocophereth-50, which affects its solubility and its interaction with the skin.

Tocophereth-5 is a versatile ingredient used in a variety of cosmetic products. Its antioxidant properties make it a valuable addition to anti-aging creams and serums, where it helps to protect the skin from damage caused by free radicals. Additionally, its skin conditioning and cleansing abilities make it a popular choice for moisturizers, cleansers, and body washes. Its unique combination of properties makes Tocophereth-5 a valuable asset in the formulation of effective and beneficial cosmetic products.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Tocophereth-5:

Antioxidant Properties

Tocophereth-5 is known for its antioxidant properties. In the context of cosmetics, this means that it helps to protect your skin from damage caused by free radicals. Free radicals are unstable molecules that can harm the cellular structures of your skin, leading to premature aging and other skin issues. By neutralizing these free radicals, Tocophereth-5 helps to maintain the health and vitality of your skin, keeping it looking youthful and radiant.

Skin Conditioning

Another official function of Tocophereth-5 is skin conditioning. This means that it helps to soften and smooth your skin, improving its overall texture and appearance. It works by forming a barrier on the skin’s surface, which helps to retain moisture and keep your skin hydrated. This can be particularly beneficial for those with dry or rough skin, as it can help to restore the skin’s natural moisture balance and promote a smoother, more supple complexion.

Cleansing

Tocophereth-5 also serves as a cleansing agent in cosmetic products. It works by helping to remove dirt, oil, and other impurities from your skin, leaving it clean and refreshed. This can help to prevent the buildup of impurities that can clog your pores and lead to breakouts, making it a valuable ingredient in facial cleansers and other skincare products.

It’s important to note that these benefits are based on the officially recognized and defined functions of Tocophereth-5. There may be other benefits and uses of this ingredient that go beyond the scope of these official functions. However, these additional benefits are not officially recognized and therefore, are not discussed in this article.

Safety Profile

Tocophereth-5 is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, like any other ingredient, it may not be suitable for everyone. Its allergenic potential is relatively low, but individuals with sensitive skin or known allergies to similar ingredients should exercise caution.

Potential side effects of topical application of Tocophereth-5 may include:

  • Minor skin irritation
  • Redness
  • Dryness

A note for women who are pregnant and/or breastfeeding – there is currently insufficient data on the safety of topically applied Tocophereth-5 during pregnancy or breastfeeding. As such, it is recommended to consult a healthcare professional for further advice.

Adverse reactions to Tocophereth-5 are not common, but it is always recommended to perform a patch test before widespread usage to ensure no adverse reaction occurs.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources including the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA), as well as other various publicly available sources.