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Ingredient Analysis: Tocopheryl Nicotinate

This page was last updated: 6 months ago. All information accurate at time of publishing.
Unlock the secrets of Tocopheryl Nicotinate (pronounced toh-co-fair-ill nih-co-tin-ate), a unique derivative of Vitamin E, as we delve into its creation, benefits, and safety in cosmetics.

What is Tocopheryl Nicotinate?

Tocopheryl Nicotinate, also known as Vitamin E Nicotinate, is a unique derivative of Vitamin E, a naturally occurring nutrient found in certain foods such as nuts, seeds, and leafy green vegetables. It is chemically composed of the ester of Tocopherol (Vitamin E) and Nicotinic Acid, hence its name. This compound is characterized by its complex chemical structure, specifically [2R-[2R*(4R*,8R*)]]-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate / [2R*(4R*,8R*)]-(.+-.)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate.

The use of Tocopheryl Nicotinate in cosmetic products dates back several decades, with its antioxidant properties being harnessed to protect the skin from environmental stressors. It is synthesized through a chemical reaction between Tocopherol and Nicotinic Acid under controlled laboratory conditions.

While it shares similarities with other Vitamin E derivatives used in cosmetics, such as Tocopheryl Acetate and Tocopheryl Linoleate, Tocopheryl Nicotinate stands out due to its unique ability to condition and protect the skin. Unlike some other derivatives, it is not simply an antioxidant but also possesses skin conditioning and protecting properties, making it a multifunctional ingredient in cosmetic formulations.

Tocopheryl Nicotinate is typically used in a wide range of cosmetic products, including but not limited to moisturizers, serums, sunscreens, and anti-aging treatments. Its versatility and beneficial properties make it a popular choice among cosmetic formulators and manufacturers.

Benefits and Uses

In this section, we will delve into the officially recognized benefits and uses of Tocopheryl Nicotinate:

Antioxidant Properties

Tocopheryl Nicotinate is recognized for its antioxidant properties. In simple terms, antioxidants are substances that help protect our skin cells from damage. They do this by neutralizing harmful molecules known as free radicals, which are produced in our skin as a result of exposure to environmental stressors like pollution and UV rays. By neutralizing these free radicals, Tocopheryl Nicotinate helps to maintain the health and integrity of our skin cells, thereby contributing to a healthier and more youthful-looking complexion.

Skin Conditioning

Another key benefit of Tocopheryl Nicotinate is its skin conditioning properties. As a skin conditioner, this ingredient works by enhancing the appearance and feel of the skin. It helps to keep the skin hydrated, soft, and smooth, thereby improving its overall texture and tone. This makes Tocopheryl Nicotinate a valuable ingredient in a variety of cosmetic products, including moisturizers, serums, and anti-aging creams.

Skin Protecting

Tocopheryl Nicotinate also serves a skin protecting function. This means that it helps to form a barrier on the skin’s surface, which protects the skin from environmental factors that can cause damage. This protective barrier not only helps to prevent moisture loss from the skin but also shields it from harmful external elements. This can be particularly beneficial for individuals with sensitive skin or those living in harsh or extreme weather conditions.

It’s important to note that these benefits are based on the officially recognized and defined functions of Tocopheryl Nicotinate. There may be other potential benefits and uses of this ingredient that go beyond the scope of these official functions. However, further research may be needed to fully understand and validate these additional benefits.

Safety Profile

Tocopheryl Nicotinate is not a banned or regulated ingredient in cosmetics. It is generally considered safe for use in cosmetic products. However, as with any ingredient, individual reactions can vary and it is always recommended to do a patch test before widespread usage.

As an antioxidant and skin conditioning agent, Tocopheryl Nicotinate is generally well-tolerated by the skin. However, potential side effects of topical application may include:

  • Minor skin irritation
  • Redness
  • Dryness

A note for women who are pregnant and/or breastfeeding – there is currently insufficient data on the safety of topical usage of Tocopheryl Nicotinate during pregnancy or breastfeeding. It is always recommended to consult a healthcare professional for further advice.

Adverse reactions to Tocopheryl Nicotinate are not common, but as with any cosmetic ingredient, they can occur. It is always recommended to do a patch test before widespread usage to ensure there is no adverse reaction.

This ingredient analysis has been commissioned by Truth In Skincare (TiS), an independent industry regulator. The analysis was conducted by a TiS-appointed industry consultant, using sources that include the CosIng (Cosmetic Ingredient Database – by the European Commission), the Personal Care Products Council (PCPC), The US Food & Drug Administration (FDA) as well as other various publicly available sources.